RECK anticorps (AA 621-832)
Aperçu rapide pour RECK anticorps (AA 621-832) (ABIN1108847)
Antigène
Voir toutes RECK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 621-832
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Specificité
- This antibody reacts with RECK.
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Protein A agarose
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Immunogène
- Recombinant RECK protein (621-832 a.a)
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store (in aliquots) at -20 °C.
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- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
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Autre désignation
- RECK / ST15
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Sujet
- A membrane-anchored glycoprotein, RECK is encoded by a RECK gene (reversion-inducing cysteine-rich protein with Kazal motifs) identified as a transformation suppressor gene. This 110 kDa protein consists of 971a.a. The protein contains protease inhibitor like domains such as the Kazal motif, and epidermal growth factor (EGF) like repeats. Takahashi et al. reported that restoration pf RECK expression in malignant cells resulted in suppression of invasive activity with a concomitant decrease in the secretion of matrix metalloproteinase-9 (MMP-9), a key enzyme involved in tumor invasion and metastasis.Synonyms: Reversion-inducing cysteine-rich protein with Kazal motifs, Suppressor of tumorigenicity 15 protein
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ID gène
- 8434
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NCBI Accession
- NP_066934
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UniProt
- O95980
Antigène
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